Type 2 Drug Semaglutide May Soon Come in Pill Form
The injectable type 2 diabetes drug semaglutide (Ozempic) may soon be available in pill form. To get there, researchers need to be sure the oral drug is as safe for the heart as the injected form. They studied 3,183 adults with type 2 diabetes ages 50 or older, including many with heart disease and/or chronic kidney disease. Those randomly given oral semaglutide were half as likely to die of heart disease and 26 percent less likely to have a stroke over about 16 months than those given a placebo. As expected, the drug also lowered blood glucose levels and body weight. And as with the injectable version, more people experienced gastrointestinal problems, including nausea and vomiting, with oral semaglutide than the placebo, but this tended to go away with time. The research brings people with type 2 diabetes a step closer to a semaglutide pill, which could make diabetes management easier for those who rely on the injected form.
Source: The New England Journal of Medicine, published online June 11, 2019