Metformin Reduces Risk of Type 2 Diabetes
Metformin, the glucose-lowering drug used to treat type 2 diabetes, can prevent the condition, too. In a 2002 landmark study of more than 3,000 people at high risk for type 2, both lifestyle changes and daily metformin use cut the risk for developing the condition. Metformin cut the risk by 31 percent, and lifestyle changes cut it by 58 percent. After 15 years, those who took metformin during the study still had a lower type 2 diabetes risk. They had a 17 to 36 percent lower risk than their peers who’d taken a placebo. This was especially true for two specific groups: those with higher average glucose levels (for example, an A1C between 6 and 6.4 percent compared with less than 6 percent) and women who had been diagnosed with gestational diabetes. If you have prediabetes, ask your health care provider if metformin might fit in with your lifestyle efforts to lower your risk for type 2.
Source: Diabetes Care, published online March 15, 2019