Diabetes Forecast

New Injectable May Help Manage Type 1


An experimental drug might help manage type 1 diabetes. The injectable drug blocks the action of glucagon, a hormone that raises blood glucose levels. In an in-hospital study, 10 adults with type 1 diabetes received a single injection of the drug, currently called REMD-477, while 11 others received a placebo injection. All ate the same food, wore continuous glucose monitors, and received intravenous insulin for five days. Participants who received REMD-477 required 26 percent less insulin by day four than they had at the start of the study. They also lowered their blood glucose by an average of 20 to 30 mg/dl for the following eight weeks after the study—without an increase in hypoglycemia (low blood glucose). Further studies are being conducted in a larger group of participants.
Source: American Diabetes Association 77th Scientific Sessions



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