Antidepressants and Your Weight
Obesity and depression often go hand in hand. Given that, it’s helpful to know the effect of antidepressant medications on weight. Researchers identified 5,932 patients in a large health care system who began taking antidepressants during 2006–2009. Over two years, weight loss occurred with just one type of antidepressant: buproprion (Wellbutrin and Zyban). Nonsmokers who took it lost an average of 2.4 pounds, compared with weight gains ranging from 2.6 pounds with venlafaxine (Effexor) to 16.2 pounds with mirtazapine (Remeron). Smokers, even those taking buproprion, gained about 6.9 pounds. The findings were significant even after adjusting for age, mental health, and other factors.
Source: The Journal of Clinical Medicine, published online April 19, 2016