Gene Injection Studied for Diabetic Neuropathy Relief
An experimental shot of a gene that helps nerves grow has shown promising results in a study of 99 adults with painful diabetic neuropathy, a complication related to frequent high blood glucose that causes pain and numbness in the arms, hands, legs, and feet. In half of the participants, the gene was injected into each leg twice, two weeks apart. The others received dummy shots. After three months, 48 percent of those who received a low dose of the gene reported at least 50 percent pain relief, versus just 17.6 percent of those who got the placebo. There were no side effects, and some patients reported pain relief for up to nine months. Pain relief was greatest among those who were not taking neuropathy medications, suggesting the gene might be a good alternative for some patients.
Source: Annals of Clinical and Translational Neurology, published online March 5, 2015