Is LADA Distinct From Type 1?
Research news from the American Diabetes Association 72nd Scientific Sessions
June 8–12, 2012 | Philadelphia, Pennsylvania
People with type 1 typically require insulin therapy at diagnosis no matter their age because their immune systems have destroyed most of the beta cells in the pancreas that make the hormone. But what about adults with malfunctioning immune systems who don't need insulin injections for six months or more? They are said to have latent autoimmune diabetes in adults (LADA), but some researchers question whether LADA is really distinct from type 1. A European study looked at 6,156 people who'd developed diabetes in adulthood, checking their weight, age, and autoantibody status at the onset of diabetes. The researchers found striking similarities in those with LADA and type 1, and a clear separation between these two conditions and type 2 diabetes. The results suggest that LADA and type 1 may be two sides of the same coin.