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Type 2 Drug Improves Glucose Control

The drug dapagliflozin, which increases the amount of glucose excreted in the urine, can improve glucose control in people with type 2 diabetes, according to a study. Researchers assigned 546 adults with type 2 diabetes and poor glucose control to one of three doses of the medication or a placebo. (People in the study were on metformin before and during the trial.) After 24 weeks, all participants taking dapagliflozin had a greater A1C reduction than those in the placebo group; the drop in A1C got larger as the dose increased. Plus, those who received the drug lost weight and decreased their waist size. However, symptoms of genital infections (but not urinary tract infections) were more common in people taking the medication. Dapagliflozin is still being tested and has not received Food and Drug Administration approval
Source: The Lancet, June 26, 2010



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